| Unlockable | How to Unlock |
| No money loss when busted | Complete the Avenging Angels missions on Staunton Island. |
| Spirit E and PJC at Staunton Island safe house | Deliver all sixteen vehicles on the list to the Love Media garage in Bedford. |
| Super Angel Bike (bulletproof) at Portland safe-house | Complete Avenging Angels missions in Portland. |
| Super Land Stalker (bulletproof) at Shoreside Vale safe-house | Complete the Avenging Angels missions in Shoreside Vale. |
| Upgraded Sanchez | Complete all ten courses in the "Bump & Grinds" at the dirt bike course in Portland. |
| Antonio costume | Successfully complete the "Making Toni" mission. |
| Avenging Angel costume | Successfully complete the "Frighteners" mission. |
| Chauffeur costume | Successfully complete the "Rollercoaster Ride" mission. |
| Cox Mascot costume | Win SlashTV two times. |
| Dragon Jumpsuit costume | Successfully complete the "Crazy 69" mission. |
| Goodfella costume | Successfully complete the "Overdose Of Trouble" mission. |
| King' Jumpsuit costume | Successfully complete all missions. |
| Overalls costume | Successfully complete "The Portland Chainsaw Masquerade" mission. |
| Sweats costume | Successfully complete the "A Walk In The Park" mission. |
| Tuxedo costume | Successfully complete the "A Date with Death" mission . |
| Underwear costume | Complete one unique jump. |
| Wise Guy costume | Successfully complete the "Shoot The Messenger" mission. |
| Extra 25 Max Health Points | Complete Level 10 in Pizza Deliveriy Missions at Joe's Pizza in Staunton Island |
| Extra 25 Max Health Points | Complete Level 10 in Noodle Delivery Missions at Noodle Punk in Portland |
| Fireproof Toni | Complete Level 12 In Firefighter Missions |
| Generate a boat Speeder at Portland Ferry Docks | Beat the game 100% |
| Generate cash from "Hogs & Cogs" | Sell 40 motorcycles in Belleville Park, Staunton Island |
| Get 10000$ | Complete all 26 unique jumps |
| Infinite Ammo | Beat the game 100% |
| Infinite Sprint | Beat Ambulance Missions Level 12 |
| Multiplayer Skins | Complete the "Driving Mr Leone" mission. |
| Code | Result |
| L1, R1, Circle, L1, R1, X, L1, R1 | Body armor |
| L1, R1, X, L1, R1, Square, L1, R1 | Full health |
| L1, R1, Square, L1, R1, Triangle, L1, R1 | Wanted level increased |
| L1(2), Triangle, R1(2), X, Square, Circle | Wanted level disabled |
| L1, Up, Left, R1, Triangle, Circle, Down, X (Note: Press Down to have your vehicle jump) | Better handling vehicles |
| Circle, Right, X, Up, Right, X, L1, Square (Repeat the code to cycle the tire sizes between large, small, and normal) | Change motorcycle tire size |
| L1(2), Left, L1(2), Right, X, Square | Destroy all cars |
| Circle, X, Down, Circle, X, Up, L1(2) | Drive on water |
| Circle(2), R1, Triangle(2), L1, Square(2) | Black traffic |
| Triangle, R1, L1, Down(2), R1(2), Triangle | Chrome traffic |
| X(2), R1, Circle(2), L1, Triangle(2) | White traffic |
| Triangle(2), R1, Square(2), L1, X(2) | Traffic lights always green |
| Square(2), R1, X(2), L1, Circle(2) | Aggressive drivers |
| R1(2), L1, R1(2), L1, Right, Circle | Pedestrians have weapons |
| L1(2), Left, L1(2), Right, Square, Triangle | Random pedestrian costumes |
| Up, Down, Circle, Up, Down, Square, L1, R1 | Clear weather |
| L1(2), Circle, R1(2), Square, Triangle, X | Sunny weather |
| Up, Down, Triangle, Up, Down, X, L1, R1 | Foggy weather |
| Up, Down, X, Up, Down, Triangle, L1, R1 | Overcast weather |
| Up, Down, Square, Up, Down, Circle, L1, R1 | Rainy weather |
| L1(2), Left, L1(2), Right, Circle, X | Faster game time |
| R1(2), L1, R1(2), L1, Down, X | Faster game play |
| R1, Triangle, X, R1, Square, Circle, Left, Right | Slower game play |
| L1(2), R1, L1(2), R1, Up, Triangle | Pedestrians attack you |
| L1(2), R1, L1(2), R1, Left, Square | Pedestrians riot |
| Down(3), Triangle(2), Circle, L1, R1 | Pedestrians follow you |
| Down(3), Circle(2), X, L1, R1 | Big head mode |
| L1(2), Left, L1(2), Right, Triangle, Circle | Spawn Rhino |
| Triangle, Circle, Down, Triangle, Circle, Up, L1(2) | Spawn Trashmaster |
| L1, Down, Left, R1, X, Circle, Up, Triangle | Commit suicide |
| L1, Up, Right, R1, Triangle, Square, Down, X (Keep breaking the law until the media attention level is displayed) | View media attention level |
| Up, Square(2), Down, Left, Square(2), Right | Weapons (tier 1) |
| Up, Circle(2), Down, Left, Circle(2), Right | Weapons (tier 2) |
| Up, X(2), Down, Left, X(2), Right | Weapons (tier 3) |
| L1, R1, Triangle, L1, R1, Circle, L1, R1 | $250,000 |
| Down(3), X(2), Square, R1, L1 | Upside down |
| X(3), Down(2), Right, L1, R1 | Upside down (alternate) |
| Triangle(3), Up(2), Right, L, R | Return to normal from upside down |
| Up(3), Triangle(2), Square, R, L | Return to normal from upside down (alternate) |
| L1, R1, L1, R1, Up, Down, L1, R1 | View game credits |